Research in Vestibular Science

Case Reports

A Case of Patient with Meniere’s Disease Who Presented Periodic Alternating Nystagmus: Jin Woo Park, Ja Won Gu, Mee Hyun Song, Dae Bo Shim; Res Vestib Sci. 2016;15(3):80-83. Published online September 15, 2016; DOI: https://doi.org/10.21790/rvs.2016.15.3.80

Abstract PDF: Periodic alternating nystagmus (PAN) is a spontaneous horizontal jerky nystagmus that reverses its direction periodically with a quiescent interval. PAN has been reported in acquired and congenital forms. The main lesion site of the acquired form of PAN has been attributed to the caudal brainstem or cerebellum. Herein we report a 63-year-old male patient with Meniere’s disease, who presented PAN during a vertigo attack. The patient demonstrated no abnormality on neurologic evaluation and brain imaging, which is different feature compared to the central or congenital form of PAN. It should be kept in mind that peripheral vestibular disorders such as Meniere’s disease can produce PAN.

Periodic Alternating Nystagmus in Patients with Cerebellar Abscess: Hyung Lee, Hyun Ah Kim; Res Vestib Sci. 2016;15(1):27-29.

Abstract PDF: Periodic alternating nystagmus (PAN) is characterized by a periodical reversal in the direction of the nystagmus. Acquired PAN is caused by lesions of the inferior cerebellar vermis, causing disinhibition of the velocity storage mechanism, which is mediated by the vestibular nuclei. An eighty-year-old woman with abscess in midline cerebellum experienced dizziness and imbalance. We observed short period PAN with 7?8 seconds.

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