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Journal of the Korean Balance Society 2008;7(1): 73-76.
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| 항 GD1b IgG 항체와 연관된 천향성 체위성 안진 1예 |
| , , , 정성해, 오건세, 신동익, 김지수 |
| 을지대학교 의과대학 신경과학교실, 대전을지대학병원 신경과1 충북대학교 의과대학 신경과학교실, 충북대학교병원 신경과2 서울대학교 의과대학 신경과학교실, 분당서울대학교병원 신경과3 |
| A Case of Apogeotropic Positional Nystagmus Associated With Anti-GD1b IgG Antibody |
| Seong Hae Jeong, Gun Sei Oh, Dong Ick Shin, Ji Soo Kim |
1Department of Neurology, Eulji University School of Medicine, Eulji University Hospital, Daejeon, Korea. mseaj@eulji.ac.kr
2Department of Neurology, Chungbuk National University, College of Medicine, Chungbuk National University Hospital, Korea.
3Department of Neurology, Seoul National University, College of Medicine, Seoul National University Bundang Hospital, Korea. |
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| ABSTRACT |
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The binding of anti-GD1b IgG antibody to the cerebellar granular area or spinocerebellar Ia fibers in the peripheral nerves may cause the prominent cerebellar ataxia, mild quadriparesis and sensory dominant neuropathy. A 31-year woman presented with severe cerebellar ataxia and prominent apogeotropic positional nystagmus/vertigo. Increased anti-GD1b antibody IgG in her serum was noted. 18F-flurodeoxyglucose positron emission tomography (FDG-PET) showed decreased uptake in cerebellum. It is the first case of central positional nystagmus with anti-GD1b IgG antibody. |
| Keywords:
Anti-GD1b IgG antibody; Apogeotropic nystagmus; Positron emission tomography |
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