A Case of Creutzfeldt-Jakob Disease Presenting Mainly with Abnormal Eye Movements

Kang,  Yeo Jeong; Kim,  Jun Hyun; Kim,  Tae Eun; Park,  Sun Ah; Lee,  Tae Kyeong

Research in Vestibular Science > Volume 13(2); 2014 > Article

Original Article

Research in Vestibular Science 2014;13(2): 53-56.

초기에 이상안구운동을 주된 증상으로 보인 크로이츠펠트-야콥병

강여정, 김준현, 김태은, 박선아, 이태경

순천향대학교 의과대학 순천향대학교부천병원 신경과학교실

A Case of Creutzfeldt-Jakob Disease Presenting Mainly with Abnormal Eye Movements

Yeo Jeong Kang, Jun Hyun Kim, Tae Eun Kim, Sun Ah Park, Tae Kyeong Lee

Department of Neurology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. xorudoc@schmc.ac.kr

ABSTRACT

Creutzfeldt-Jakob disease (CJD) is a human prion disease with rapidly progressive neurodegeneration. The major clinical manifestations of CJD include mental deterioration, myoclonus, cerebellar dysfunction, and neuro-ophthalmic symptoms and signs. However, abnormal eye movements as an early sign of CJD are rare. We report a 49-year-old man with periodic alternating nystagmus in early disease course.

Keywords: Creutzfeldt-Jakob syndrome; Fixation, ocular; Nystagmus, pathologic