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- Case Report Asymmetric Audiovestibular Dysfunction in Patients With Systemic Aminoglycoside Treatment
- Jae Hong Park, Yoon Chan Rah, Ji Soo Kim, Ja Won Koo
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DOI: https://doi.org/
1Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. jwkoo99@snu.ac.kr 
2Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Research Center for Sensory Organs, Medical Research Center, Seoul National University, Seoul, Korea.
2Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Research Center for Sensory Organs, Medical Research Center, Seoul National University, Seoul, Korea.
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Abstract
Since the characteristics of aminoglycoside ototoxicity is typically bilaterally symmetric progression of cochlea-vestibular dysfunction, a unilateral involvement has rarely been reported. However, ototoxicity can be asymmetric or focal after systemic aminoglycoside treatment. The authors report 2 cases of asymmetric or focal audiovestibular deficits in patients treated with systemic aminoglycoside. In such cases, further investigations are also necessary to rule out other possible causes of unilateral sensorineural hearing loss such as cerebellopontine angle tumors.
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