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Research in Vestibular Science > Volume 12(2); 2013 > Article
Research in Vestibular Science 2013;12(2): 62-66.
아미노글리코사이드 전신투여 환자에서 나타난 비대칭적 청각전정장애
, , , 박재홍1, 나윤찬1, 김지수2, 구자원1,3
서울대학교 의과대학 분당서울대학교병원 1이비인후과학교실, 2신경과학교실, 3서울대학교 의학연구원 감각기관연구소
Asymmetric Audiovestibular Dysfunction in Patients With Systemic Aminoglycoside Treatment
Jae Hong Park, Yoon Chan Rah, Ji Soo Kim, Ja Won Koo
1Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. jwkoo99@snu.ac.kr
2Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Research Center for Sensory Organs, Medical Research Center, Seoul National University, Seoul, Korea.
ABSTRACT
Since the characteristics of aminoglycoside ototoxicity is typically bilaterally symmetric progression of cochlea-vestibular dysfunction, a unilateral involvement has rarely been reported. However, ototoxicity can be asymmetric or focal after systemic aminoglycoside treatment. The authors report 2 cases of asymmetric or focal audiovestibular deficits in patients treated with systemic aminoglycoside. In such cases, further investigations are also necessary to rule out other possible causes of unilateral sensorineural hearing loss such as cerebellopontine angle tumors.
Keywords: Aminoglycosides; Ototoxicity; Vestibular schwannoma
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