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Research in Vestibular Science > Accepted Articles
Cerebellar ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS) 환자에서 뇌 대사감소
Byoung-Min Jeong1, Byoung-Soo Shin1, Man-Wook Seo1, Ji-Yun Park2, Hwan-Jeong Jeong3, Sun-Young Oh1
1Department of Neurology, Chonbuk National University Medical School , Jeon-ju city, Korea
2Department of Neurology, Ulsan University Hospital , Ulsan city, Korea
3Department of Nuclear Medicine, Chonbuk National University Medical school, Jeoj-ju city, Korea
Correspondence  Sun-Young Oh ,Tel: 063-250-1590, Fax: 063-251-9363, Email: ohsun@jbnu.ac.kr
Received: November 4, 2017;  Accepted: November 29, 2017.  Published online: November 29, 2017.
ABSTRACT
Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a slowing progressive ataxic disorder characterized by bilateral vestibulopathy, cerebellar ataxia and somatosensory impairment. Autonomic dysfunction is recently considered as a core feature in CANVAS in addition to these symptoms. In most cases, patients with CANVAS show cerebellar atrophy in brain imaging, but some cases show minimal or no atrophy of cerebellum. Brain 18F-FDG PET study can be a complimentary tool to diagnosis CANVAS in cases of no structural abnormality such as cerebellar atrophy. Hereby, we present a case of CANVAS with minimal atrophy of cerebellum but showing a prominent hypometabolism in cerebellum, thalamus and posterior cingulate cortex in 18F-FDG PET.
Keywords: CANVAS; cerebellar ataxia; autonomic failure; 18F-FDG PET
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Brain Hypometabolism in Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome  2017 December;16(4)
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