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양성돌발성두위현훈에서 혈소판 지표의 역할에 대한 연구.
Byeong Min Lee1, Chae Dong Yim1, Dong Gu Hur2, Seong-Ki Ahn1
1경상대학교병원 이비인후과, 진주시, Korea
2창원경상대학교병원 이비인후과, 창원시, Korea
3경상대학교 건강과학연구원, 진주시, Korea
Correspondence  Seong-Ki Ahn ,Tel: 055-750-8176, Fax: --, Email: skahn@gnu.ac.kr
Received: October 29, 2021;  Accepted: November 22, 2021.  Published online: November 22, 2021.
Objective:   Benign paroxysmal positional vertigo (BPPV) is one of the most common causes of dizziness. Even though the etiology of BPPV has been widely studied, the exact mechanism remains still unclear. One of the possible factors explaining the pathophysiology of BPPV is ischemia of vestibule. In the present study, we have focused on the platelet (PLT) indices including mean platelet volume (MPV), platelet distribution width (PDW), and platelet crit (PCT) to assess a risk of vestibule ischemia causing BPPV.
Method:   From January 2021 to March 2021, a retrospective review was performed on 39 patients diagnosed with BPPV through vestibular nystagmography. For each PLT indices, a comparative analysis was conducted between the patient group and control group.
Results:   In BPPV patients, there were no significant differences when the PLT, MPV, PDW and PCT values were compared between the study and control group. Rather, the control group showed higher PDW value than the study group.
Conclusion:   Ischemia of vestibule is one of the well-known causes of BPPV, but the current study showed that BPPV cannot be explained by the vestibule ischemia itself. Further studies are needed to identify the potential of ischemia regarding BPPV by approaching with other methods with a large study group.
Keywords: BPPV; ischemia; vestibule; platelet
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