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J Korean Bal Soc > Volume 6(2); 2007 > Article
Journal of the Korean Balance Society 2007;6(2): 234-238.
특발성 호산구 증가증에서 발생한 동안신경 마비 2예
임미혜, 신병수, 김영현, 오선영
전북대학교 의과대학 신경과학교실
Third Nerve Palsy in Idiopathic Hypereosinophilic Syndrome: Report of Two Cases
Mi Hye Lim, Byoung Soo Shin, Young Hyun Kim, Sun Young Oh
Department of Neurology, Chonbuk National University College of Medicine, Korea. ohsun@chonbuk.ac.kr
The idiopathic hypereosinophilic syndrome (IHES) is a heterogenous spectrum of disorders, characterized by a long lasting hypereosinophilia without identifiable underlying cause and by the presence of various end-organ dysfunction. The neurologic manifestations of IHES can be encephalopathy, organic psycho syndrome and polyneuropathy and in rare cases polymyositis. Central nervous system involvement is the second mostclinically important complication of the hypereosinophilic syndrome as it is associated with chronic disability and a poor prognosis. In this report, we describe two patients of IHES who presented anisolated third nerve palsy with pupillary involvement and were improved by corticosteroid therapy. They satisfied the criteria of IHES and the third cranial nerve was the only site of neurologic involvement. Early recognition of neurologic involvement in IHES and prompt treatment could lead to good outcome.
Keywords: Hypereosinophilic syndrome; Third nerve palsy
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