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J Korean Bal Soc > Volume 6(2); 2007 > Article
Journal of the Korean Balance Society 2007;6(2): 150-154.
가역적 뇌량 팽대 병변을 동반한 리튬 유발성 하향안진
김동욱, 이승한, 정현정, 강경욱
전남대학교 의과대학 신경과학교실
Lithium-Induced Downbeat Nystagmus with Reversible Splenial Lesion
Dong Uk Kim, Seung Han Lee, Hyun Jung Jung, Kyung Wook Kang
Department of Neurology, Chonnam National University Medical School, Korea. nrshlee@chonnam.ac.kr
ABSTRACT
Lithium is recognized as a cause of reversible or permanent downbeat nystagmus. Many patients who were treated with lithium for psychiatric illness developed downbeat nystagmus and other neurological manifestations. Reversible splenial lesions of corpus callosum are commonly seen on diffusion-weighted imaging (DWI) in various neurological disorders including metabolic/toxic encephalopathy, encephalitis, patients with epilepsy receiving antiepileptic drugs. Herein, we report a patient with reversible downbeat nystagmus, disturbance of smooth pursuit, and gait ataxia who was treated with lithium. Also, we can observe reversible splenial lesion of corpus callosum on DWI in this patient.
Keywords: Lithium; Downbeat nystagmus; Corpus callosum; Ataxia
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